The Heritage Softail Nostalgia cruiser is from the collection of actor Federico Castelluccio, who played the character Furio Giunta on the HBO series. It is signed by 20 members of the cast including James Gandolfini, Lorraine Bracco and Michael Imperioli.
A portion of the proceeds from the sale will go to the Little Baby Face Foundation, a charitable organization that provides corrective surgery for children born with facial deformities.
The motorcycle is a white 1994 Harley-Davidson FLSTN with 3,790 miles.
In addition to the bike, the winner of the auction will dine with Castelluccio and other celebrities at a private Italian restaurant in Manhattan.
The auction will close on April 16 and begin with an opening bid of US$10,000. The auction is being held by Steiner Marketplace at http://www.steinermarketplace.com/.